منابع مشابه
Efficacy of sustained-release radioprotective drugs in vivo.
In previous publications from this laboratory we suggested the use of radioprotective drugs in a sustained-release form as a practical way to cope with their high toxicity and quick metabolism and excretion. Cysteine and cysteamine, well-established radioprotectants, were used as model drugs and compressed at various concentrations (0-65%) into an insoluble tablet matrix, composed of ethylcellu...
متن کاملRadioprotective Efficacy of Lutein in Ameliorating Electron Beam Radiation-induced Oxidative Injury in Swiss Albino Mice
Background: Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation. This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice.Methods: The optimized dose of the compound was orally administered for 15 days, and ...
متن کاملRadioprotective Properties of Baicalein
Radiation is an important source of free radicals in living systems. Ionizing radiations such as γ-rays exert their biological effects through generation of reactive oxygen species and the resultant damage to DNA and cellular membranes. Several natural compounds, especially with antioxidant abilities are known to be radioprotective. Baicalein (5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one), a...
متن کاملRadioprotective potential of ginseng.
A majority of potential radioprotective synthetic compounds have demonstrated limited clinical application owing to their inherent toxicity, and thus, the seeking of naturally occurring herbal products, such as ginseng, for their radioprotective capability has become an attractive alternative. In general, ginseng refers to the roots of the species of the genus Panax. As a medicinal herb, ginsen...
متن کاملEvaluation of radioprotective efficacy and possible mechanism of action of Aloe gel.
The present study was undertaken to determine the optimum effective dose, dose reduction factor (DRF) and possible mechanism of action of Aloe gel. Three different doses of gel (250, 500 and 750 mg/kg body weight) were tested against 8 Gy induced damage in Swiss albino mice. A dose of 750 mg/kg body weight of Aloe was found the most effective while, 250 mg/kg body weight was the least effective...
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ژورنال
عنوان ژورنال: Acta Radiologica: Therapy, Physics, Biology
سال: 1964
ISSN: 0567-8064
DOI: 10.3109/02841866409134135